Vertex Pharmaceuticals has a new non-opioid pain medication called VX-548 (Suzetrigine); per https://news.vrtx.com/news-releases/news-release-details/vertex-announces-fda-acceptance-new-drug-application-suzetrigine they expect FDA action on their application in January.

In 2020, 12.7 million people were prescribed opioids in the US alone ( https://meps.ahrq.gov/data_files/publications/st552/stat552.shtml ); 500k would represent <5% of the market.

I learned about this medication through a person with inside information and therefore will not trade on this market.

Related market: https://manifold.markets/PGeyer/pain-relief-vs-addiction-will-verte